Finding the right organic asparagus extract powder ingredients to buy — especially if you’re searching for asparagus extract powder ingredients online — is not always easy, but with ETAS enzyme treated asparagus it is.

ETAS is a proprietary ingredient derived from the tough lower portion of asparagus stalks, which has the unique ability to increase the production of heat shock protein 70 (HSP70).* Regarding asparagus extract powder health benefits, double-blind, placebo-controlled research has shown ETAS enzyme-treated asparagus effectively:

Increases quality of sleep*[1]

Alleviates occasional stress by improving
heart rate variability*[2]

Raises cognitive performance, reduces
fatigue, and improves the stress response*[3],[4],[5]

The extraction process used to create ETAS asparagus extract powder results in unique hydroxymethyl furfural derivatives — particularly asfural — that are not contained in raw asparagus extract.

MECHANISM OF ACTION

Asparagus Extract Powder Benefits

ETAS asparagus extract powder works by increasing the production of HSP70 — an intracellular protein produced naturally by the body when it encounters a stressor, such as extreme heat.*[6]

HSP70 has many beneficial functions. It repairs damaged cells, tips the balance from excitatory cytokines to inhibitory ones and serves as an antioxidant.*[7],[8],[9]  Unfortunately, the heat shock response to stressors of all kinds decreases with age.[10],[11]  Human clinical research has shown that ETAS significantly increases the expression of HSP70 at a dosage of 100 mg elemental ETAS asparagus extract powder per day.*[12] (The commercially available form of ETAS powder is 50% elemental ETAS, requiring a dosage of 200 mg per day.)

What is HSP? (Heat Shock Protein)

• All proteins need to be folded to work correctly

• HSP helps such protein folding as “chaperone” by stabilizing new proteins to ensure correct folding, or by helping to refold proteins that were damaged by the cell stress.

• HSP is found in virtually all living organisms, from bacteria to humans.




Three Tangible Effects

What is "Chaperone"?

HSP expression and ETAS function mechanism

The safety of ETAS is assured by in vitro, animal and clinical studies.

Regulatory Toxicology and pharmacology: submitted

Active Components

Several active components are identified in ETAS for HSP-induction, and ETAS is standardized with the component group “Asparaprolines” asparagus-derived proline-containing 3-alkyldiketopiperazines”.